| dc.description.abstract |
Abstract; Background; ; Previous studies have shown that participants in emergency research may not understand the research and therefore may not make informed decisions to participate. Little is documented about motivation for research participation in randomized clinical trials in emergency obstetric and newborn care. Conducted among survivors of severe obstetric complications, this study sought to assess beliefs, perceptions and values as well as motivation and willingness for participation in research.; Methods; ; This was a qualitative study conducted among 18 survivors of severe obstetric complications who were attending the post-natal clinic of Kawempe National Referral Hospital, Uganda. The participants were contacted 6–8 weeks after surviving severe obstetric complications during pregnancy or childbirth. Eighteen in-depth interviews were conducted from June 1 to July 6, 2019. The issues explored included interviewees’ perceptions and beliefs regarding 1) what constitutes clinical trial research in emergence obstetric and newborn care, 2) the purpose and necessity to conduct such research, 3) how emergency research-related information should be delivered to potential participants and their caregivers, 4) why women would be willing and motivated to participate in this type of research, and 5) the potential benefits and risks to research participants. Data were analyzed according to themes using the constant comparative method.; Findings:; ; Many respondents were potentially willing to participate in research during obstetric emergencies, even when there was no possibility of material or therapeutic benefit, provided there was reasonable assurance that there would be no harm to them or (more especially) to their babies. Both solidarity and communitarian consent were important influences on motivation to participate in clinical trials in emergency obstetric care. Motivation to participate in research was partly related to the desire to access care, to contribute to knowledge about pregnancy complications, to possibility of material or therapeutic benefit, to perceived low level of risk particularly to the baby, to trust in the investigators and to opportunity to receive research results.; Conclusion; ; Solidarity, communitarian consent, perceived level of potential risk, possibility of benefit and trust in the investigators were the major potential motivators for participation in research in the emergency obstetric and newborn care context. |
|