Uganda: Recent submissions

Now showing items 181-200 of 1924

Barriers and facilitators for transitioning of young people from adolescent clinics to adult ART clinics in Uganda: Unintended consequences of successful adolescent ART clinics

Scovia Nalugo Mbalinda • Sabrina Bakeera-Kitaka • Derrick Lusota Amooti • Eleanor Namusoke Magongo • Philippa Musoke • Kaye K Dan (2020)

Abstract; BackgroundThere is a growing number of adolescents and young adults with HIV who require transfer of care from pediatric/ adolescent clinics to adult ART clinic. Currently, adolescents are largely in the ...
Determinants of Uptake of Malaria Preventive Interventions among Pregnant Women in Eastern Uganda

Solomon Tsebeni Wafula • Hilbert Mendoza • Aisha Nalugya • David Musoke • Peter Waiswa (2020)

Abstract; Background Consistent use of insecticide-treated nets (ITNs) and intermittent preventive treatment in pregnancy (IPTp) have been recommended as cost-effective interventions for malaria prevention during ...
Apparent Density, Trypanosome Infection Rates and Host Preference of Tsetse Flies in the Sleeping Sickness Endemic Focus of North-Western Uganda

Robert Opiro • Robert Opoke • Harriet Angwech • Esther Nakafu • Francis A. Oloya • Geoffrey Openy • Moses Njahira • Mercy Macharia • Richard Echodu • Geoffrey M. Malinga • Elizabeth A. Opiyo (2020)

Abstract; Background: African trypanosomiasis, caused by protozoa of the genus Trypanosoma and transmitted by the tsetse fly, is a serious parasitic disease of humans and animals. Reliable data on the vector ...
Methylome-wide analysis reveals epigenetic marks associated with resistance to tuberculosis in HIV-infected individuals from East Africa

Catherine M. Stein • Penelope Bencheck • Jacquelaine Bartlett • Robert P. Igo • Rafal S. Sobota • Keith Chervenak • Harriet Mayanja-Kizza • C. Fordham von Reyn • Timothy Lahey • William S. Bush • W. Henry Boom • William K. Scott • Carmen J. Marsit • Giorgio Sirugo • Scott M. Williams (2020)

Background: Tuberculosis (TB) is the most deadly infectious disease globally and highly prevalent in the developing world, especially sub-Saharan Africa. Even though a third of humans are exposed to Myocbacterium tuberculosis ...
RTS,S malaria vaccine pilot studies: addressing the human realities in large-scale clinical trials

Machteld van den Berg • Bernhards Ogutu • Nelson Sewankambo • Nikola Biller-Andorno • Marcel Tanner (2019)

Abstract; A malaria vaccine as part of the integrated malaria control and elimination efforts will have a major impact on public health in sub-Sahara Africa. The first malaria vaccine, RTS,S, now enters pilot ...
Effectiveness of Peer-supervision on Paediatric Fever Treatment among Registered Private Drug Sellers in East-Central Uganda: An Interrupted Time Series Analysis

Arthur Bagonza • Freddy Kitutu • Stefan Peterson • Andreas M rtensson • Milton Mutto • Phyllis Awor • David Mukanga • Henry Wamani (2020)
Mycobacterium Tuberculosis Thymidylate Kinase is A Potential 2 Diagnostic Biomarker for Pulmonary Tuberculosis

Janet Peace Babirye • Charles Drago Kato • Fredrick Lutwama • Carol Musubika • Rose Nabatanzi • Misaki Wayengera (2020)

Abstract; Diagnosis of pulmonary tuberculosis (PTB) in context of HIV infection remains challenging due 25 to the paucibacillary nature of the disease. Mycobacterium tuberculosis thymidylate kinase 26 (TMKmt) has ...
The contribution of rare variation to prostate cancer heritability

Nicholas Mancuso • Nadin Rohland • Kristin A. Rand • Arti Tandon • Alexander Allen • Dominique Quinque • Swapan Mallick • Heng Li • Alex Stram • Xin Sheng • Zsofia Kote-Jarai • Douglas F. Easton • Rosalind A. Eeles • Loic Le Marchand • Alex Lubwama • Daniel O. Stram • Stephen Watya • David V. Conti • Brian E. Henderson • Christopher A. Haiman • Bogdan Pasaniuc • David Reich (2015)

Although genome-wide association studies (GWAS) have found more than a hundred common susceptibility alleles for prostate cancer, the GWAS reported variants jointly explain only 33% of risk to siblings, leaving the majority ...
REASONS WHY PATIENTS BYPASS LOWER LEVEL PUBLIC FACILITIES: A CROSS SECTIONAL STUDY FROM UGANDA

SAMUEL OKORI • INNOCENT BESIGYE • JANE FRANCIS NAMATOVU (2019)

Abstract; Background; ; The quality of services in Uganda at higher level health facilities are usually affected negatively by congestion when patients bypass care from their primary care health facilities (PCHF). ...
Trends and correlates of sexually transmitted infections among sexually active Ugandan female youths: evidence from three demographic and health surveys, 2006-2016

Veronicah Masanja • Solomon Tsebeni Wafula • Tonny Ssekamatte • John Bosco Isunju • Richard K Mugambe • Guido Van Hal (2020)

Abstract; Background: Female adolescents and young women have the highest risk of curable sexually transmitted infections (STIs) globally. Data on the prevalence of STIs among young women in Uganda are limited. In ...
Effect of nutrition education on dietary diversity score of type 2 diabetes patients

Robert Mutagwanya • Christine Magala Nyago • Fredrick Nelson Nakwagala (2020)

Abstract; Background: Consumption of a varied diet reduces the risk of developing a deficiency or excess of any one nutrient. One of the three corner stones of diabetes management is diet and therefore, dietary ...
Exploring barriers and facilitators to integrated hypertension-HIV management in Ugandan HIV clinics using the Consolidated Framework for Implementation Research (CFIR)

Martin Muddu • Andrew K. Tusubira • Brenda Nakirya • Rita Nalwoga • Fred C. Semitala • Ann R. Akiteng • Jeremy I Schwartz • Isaac Ssinabulya (2020)

Abstract; BackgroundPersons Living with HIV (PLHIV) receiving antiretroviral therapy have increased risk of cardiovascular disease (CVD). Integration of services for hypertension (HTN), the primary CVD risk factor, ...
The in vitro Efficacy of Two Microbial Strains and Physicochemical Effects on their Aflatoxin Decontamination in Poultry Feeds

Zakia Tebetyo • Paul Bogere • Margaret M. Nabulime • Archileo N. Kaaya • Benoit Gnonlonfin • Mohammed Ntale • Jesca Nakavuma (2020)

Abstract; Background: Contamination of animal feeds with aflatoxigenic fungi is a challenge to livestock farmers worldwide. Aflatoxins are very toxic fungal metabolites that are associated with carcinogenic, ...
Barriers to access and utilisation of HIV/STIs prevention and care services among trans-women sex workers in the greater Kampala metropolitan area, Uganda.

Tonny Ssekamatte • John Bosco Isunju • Naomi Muyanga • Esther Buregyeya • Richard K Mugambe • Rhoda K. Wanyenze • Justine Nnakate Bukenya (2020)

Abstract; BackgroundTrans-women sex workers bear the greatest brunt of HIV and other sexually transmitted infections (STI). Trans-women are 49 times more at risk of HIV infections compared to the general population. ...
A sister lineage of the Mycobacterium tuberculosis complex discovered in the African Great Lakes region

Jean Claude Semuto Ngabonziza • Chloé Loiseau • Michael Marceau • Agathe Jouet • Fabrizio Menardo • Oren Tzfadia • Rudy Antoine • Esdras Belamo Niyigena • Wim Mulders • K. Fissette • Maren Diels • Cyril Gaudin • Stéphanie Duthoy • Willy Ssengooba • Emmanuel André • Michel Kaswa • Yves Mucyo Habimana • Daniela Brites • Dissou Affolabi • Jean Baptiste Mazarati • Bouke C. de Jong • Leen Rigouts • Sebastien Gagneux • Conor J. Meehan • Philip Supply (2020)

The human- and animal-adapted lineages of the Mycobacterium tuberculosis complex (MTBC) are thought to have clonally expanded from a common progenitor in Africa. However, the molecular events that accompanied this emergence ...
Socio-emotional and adaptive behaviour after severe anaemia in pre-schoolers at Lira Regional Referral Hospital, Uganda: a cross sectional study.

Andrew Sentoogo Ssemata • Robert O. Opoka • John M. Ssenkusu • Noeline Nakasujja • Chandy C. John • Paul Bangirana (2020)

Abstract; Background: Severe anaemia is a global public health challenge commonly associated with morbidity and mortality among children <5 years of age in Sub-Saharan Africa. However, less is known about the ...
Clinical characteristics and primary management of patients diagnosed with prostate cancer between 2015 and 2019 at the Uganda Cancer Institute

Paul Katongole • Sande J. Obondo • Mulumba Yusuf • Moses Joloba • Steven J Reynolds • Nixon Niyonzima (2020)

Background. Prostate cancer is the second most common cancer among men in Uganda, with over 2086 incident cases in 2018. This study9s objective was to report the clinical characteristics and primary management of men ...
No evidence for association with APOL1 kidney disease risk alleles and Human African Trypanosomiasis in two Ugandan populations

Magambo Phillip Kimuda • Harry Noyes • Julius Mulindwa • John Enyaru • Vincent P. Alibu • Issa Sidibé • Dieudonné Mumba • Christiane Hertz-Fowler • Annette MacLeod • Özlem Tastan Bishop • Enock Matovu (2017)

Background: Human African trypanosomiasis (HAT) manifests as an acute form caused by Trypanosoma brucei rhodesiense (Tbr) and a chronic form caused by Trypanosoma brucei gambiense (Tbg). Previous studies have suggested a ...
Diarrhoeagenic Escherichia coli isolated from children with acute diarrhoea at Rakai hospital, Southern Uganda

Fredrick Masiga • Edgar Kigozi • Christine Florence Najjuka • Henry Kajumbula • David Kateete (2020)

Abstract; Background: Diarrhoeagenic Escherichia coli (DEC) is a leading cause of childhood diarrhoea in the developing countries. However, there is scanty information on DEC and its association with childhood ...
Low Proportion of Women who came knowing their HIV Status at First Antenatal Care Visit, Uganda, 2012-2016: A Descriptive Analysis of Surveillance Data

Miriam Nakanwagi • Lilian Bulage • Benon Kwesiga • Alex Riolexus Ario • Doreen Agasha Birungi • Ivan Lukabwe • John Bosco Matovu • Geoffrey Taasi • Linda Nabitaka • Shaban Mugerwa • Joshua Musinguzi (2020)

Abstract; Background: HIV testing is the cornerstone for HIV care and support services, including Prevention of Mother to Child Transmission of HIV (PMTCT). Knowledge of HIV status is associated with better ...

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